Selenium is an essential trace mineral that supports several core systems tied to men’s sexual health—especially hormone balance, antioxidant defense, thyroid function, and sperm quality. It is a strong foundation nutrient because it helps reduce oxidative stress and supports thyroid and testosterone physiology, both of which can influence libido, mood/stress tolerance, and overall sexual function.

Selenium supports men’s sexual health mainly by powering key antioxidant enzymes (e.g., glutathione peroxidase, thioredoxin reductase) that help reduce oxidative stress and inflammation—factors that can affect vascular function, nerve signaling, and sexual stamina—while also supporting thyroid hormone metabolism and protecting thyroid tissue, which may indirectly influence arousal and the stress–arousal loop that can worsen premature ejaculation (PE). It’s also associated with improved sperm quality and overall male reproductive function.

Vitamin D3 (cholecalciferol) is a fat-soluble vitamin and hormone-like nutrient that supports male sexual health by influencing testosterone physiology, mood/stress resilience, and neuromuscular function—all factors that can shape arousal control and sexual performance. Maintaining healthy Vitamin D status can help support the foundational biological drivers that often overlap with premature ejaculation, such as stress sensitivity, low libido, and hormonal imbalance.

Vitamin D3 supports men’s sexual health through hormonal and neuropsychological pathways: adequate Vitamin D status is associated with healthier testosterone function, supports endothelial and neuromuscular performance, and plays a role in mood regulation and stress response—which can influence arousal control and the stress–arousal loop that may worsen premature ejaculation (PE). It is a foundational support nutrient within a men’s sexual health stack, especially for individuals who may be Vitamin D insufficient.

Zinc is an essential mineral that plays a central role in male sexual health, supporting testosterone production, sperm quality, and prostate function. Because zinc is also involved in neurotransmitter signaling and stress response, it can be a valuable foundational nutrient in men’s performance supplementation. Optimizing zinc status may help support libido, hormonal balance, and overall sexual resilience—factors that can influence ejaculatory control.

Zinc supports men’s sexual health through hormonal, reproductive, and prostate pathways: it’s required for healthy testosterone metabolism, contributes to sperm production and quality, and is highly concentrated in the prostate, where it supports normal function and local immune balance. Zinc also influences neurotransmitter activity and stress resilience, which can affect arousal dynamics.

Lycopene is a potent antioxidant carotenoid found in tomatoes and other red fruits, best known for supporting prostate health and overall cellular protection. In men’s sexual health supplementation, it’s most relevant as a prostate-focused antioxidant that may support comfort and confidence—especially when sexual wellbeing overlaps with prostate inflammation or urinary symptoms.

Lycopene concentrates in prostate tissue and provides antioxidant and anti-inflammatory support, which is why it’s frequently studied in the context of prostate health and male wellbeing. By helping reduce oxidative stress and supporting prostate comfort, lycopene may indirectly improve aspects of sexual confidence and performance.

Saw Palmetto (Serenoa repens) is a botanical extract best known for supporting men’s prostate and urinary function, which can indirectly benefit sexual wellbeing by improving comfort, nighttime urination, and overall confidence. It can be relevant in a men’s sexual health stack when PE is accompanied by prostate-related symptoms or when overall male performance is impacted by urinary discomfort.

Saw palmetto’s primary mechanism is support of prostate tissue and urinary flow, likely via modulation of androgen metabolism (commonly discussed as 5α-reductase/DHT-related pathways) and local inflammation in the prostate, which can improve urinary symptoms and quality of life—factors that may indirectly support sexual confidence and performance.

Plant sterols (phytosterols) are naturally occurring compounds found in plants that are widely used to support heart health and cholesterol balance. In men’s health supplementation, they’re also commonly included for prostate and urinary support, which can indirectly benefit sexual wellbeing by improving comfort, confidence, and nighttime urination. They can be a useful when sexual concerns overlap with prostate-related symptoms.

Plant sterols help reduce intestinal absorption of cholesterol, supporting vascular health, and certain sterols—especially beta-sitosterol—are studied for supporting urinary flow and prostate comfort, which can improve quality of life in men and indirectly support sexual confidence and performance. Support cardiometabolic + prostate/urinary health.